Thanks for the heads up. A simpler explanation on why does ketamine works: because you perceive the world differently: in color.
People who undergo depression don't see the world as appealing. Just change their life or their perception of the world, and you will see how their depression improves.
It's the same with MDMA and other drugs. But as you said, it's so good that a lot of people get addicted. Hopefully the research on this subject makes headway with microdosing. I hope that medicine can take the lead on this soon to help so many people.